SCHEMBL11079690

SCHEMBL11079690

Nc1ccc(S(=O)(=O)c2ccc(N)c(Cl)c2Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
HTR6 P50406 5/20 0.54
TSHR P16473 4/20 0.54
CYP3A4 P08684 3/20 0.54
LMNA P02545 1/20 0.54
MPO P05164 1/20 0.54
CYP2C9 P11712 1/20 0.54
ALDH1A1 P00352 4/20 0.52
PKM P14618 1/20 0.52
PRMT1 Q99873 2/20 0.42
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42
CA7 P43166 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL927344 0.77 HTR6 (0.58) MEN1KMT2AHTR6TSHRCYP3A4
SCHEMBL7189713 0.76 HSD11B1 (0.64) MEN1KMT2AHTR6TSHRCYP3A4
SCHEMBL17774709 0.75 HTR6 (0.62) MEN1KMT2AHTR6TSHRCYP3A4
SCHEMBL1703357 0.75 HTR6 (0.60) MEN1KMT2AHTR6TSHRCYP3A4
SCHEMBL8003877 0.74 HTR6 (0.54) MEN1KMT2AHTR6TSHRCYP3A4
SCHEMBL28457862 0.74 CA2 (0.52) MEN1KMT2ATSHRCYP3A4LMNA
SCHEMBL17774688 0.73 MEN1 (0.63) MEN1KMT2AHTR6TSHRCYP3A4
SCHEMBL11214449 0.73 MEN1 (0.63) MEN1KMT2AHTR6TSHRCYP3A4
SCHEMBL30523470 0.72 AURKA (0.44) MEN1KMT2ATSHRCYP3A4CYP2C9
SCHEMBL11362089 0.72 AURKA (0.44) MEN1KMT2ATSHRCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4487894-A REACTING POLYEPOXIDES WITH POLYIMIDE DIANHYDRIDE AND POLYIMIDE DIAMINE PLASTICS ENGINEERING COMPANY (US) 1984-12-11 US disclosed