Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | AGO2 | Q9UKV8 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902259 | 0.84 | GAA (0.44) | HTR6TSHRCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL927344 | 0.77 | HTR6 (0.58) | HTR6TSHRLMNAMPOCYP3A4 | |
| SCHEMBL7865326 | 0.76 | HKDC1 (0.57) | HTR6TSHRLMNAMPOCYP3A4 | |
| SCHEMBL17774709 | 0.75 | HTR6 (0.62) | HTR6TSHRLMNAMPOCYP3A4 | |
| SCHEMBL1703357 | 0.75 | HTR6 (0.60) | HTR6TSHRLMNAMPOCYP3A4 | |
| SCHEMBL11079690 | 0.74 | MEN1 (0.55) | HTR6TSHRLMNAMPOCYP3A4 | |
| SCHEMBL27800252 | 0.74 | AURKA (0.50) | TSHRLMNACYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10683147 | 0.74 | HKDC1 (0.71) | HTR6TSHRLMNAMPOCYP3A4 | |
| SCHEMBL8852806 | 0.73 | HTR6 (0.56) | HTR6TSHRALDH1A1PKMHKDC1 | |
| SCHEMBL11029613 | 0.73 | PKM (0.47) | HTR6TSHRLMNAMPOCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023168-A4 | FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT | US NAVY (US) | 2000-12-20 | — | — | EP | disclosed |
| EP-1023168-A1 | FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999017928-A1 | FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT | THE GOVERNMENT OF THE UNITED STATES, REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1999-04-15 | — | — | WO | disclosed |