Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095729 | 0.83 | RAB9A (0.39) | RAB9AMAPTTDP1KDM4EPOLB | |
| SCHEMBL11088824 | 0.83 | RAB9A (0.39) | RAB9AMAPTTDP1KDM4EPOLB | |
| SCHEMBL11083190 | 0.81 | HTT (0.46) | KCNA5TDP1KDM4EPOLBMEN1 | |
| SCHEMBL11089868 | 0.76 | ALDH1A1 (0.56) | RAB9AKDM4EPOLBHTTALDH1A1 | |
| SCHEMBL11087332 | 0.76 | ALDH1A1 (0.37) | KCNA5KDM4EHTTALDH1A1KAT6A | |
| SCHEMBL11085124 | 0.71 | PTGES2 (0.44) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL970204 | 0.71 | TRPV4 (0.42) | KDM4EHTTALDH1A1KAT6AHPGD | |
| SCHEMBL15461576 | 0.71 | EPAS1 (0.45) | KDM4EKMT2AHTTALDH1A1HPGD | |
| SCHEMBL24791572 | 0.68 | RAB9A (0.48) | RAB9AMAPTTDP1KDM4EPOLB | |
| SCHEMBL10351908 | 0.68 | RAB9A (0.48) | RAB9AKCNA5MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033984-B1 | NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-06-06 | — | — | EP | disclosed |
| US-4379157-A | Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-04-05 | — | — | US | disclosed |
| EP-0033984-A1 | New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-08-19 | — | — | EP | disclosed |