Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116471 | 0.85 | PI4KB (0.43) | CNR2THRBL3MBTL1HCAR1KDM2B | |
| SCHEMBL21310911 | 0.79 | ALDH1A1 (0.52) | L3MBTL1HCAR1ALDH1A1TP53RPS6KB1 | |
| SCHEMBL2361982 | 0.76 | TP53 (0.43) | L3MBTL1HCAR1ALDH1A1TP53PRKACA | |
| SCHEMBL17582784 | 0.76 | RPS6KB1 (0.48) | L3MBTL1HPGDALDH1A1TP53RPS6KB1 | |
| SCHEMBL2362323 | 0.72 | CYP11B2 (0.50) | L3MBTL1HCAR1GAAALDH1A1TP53 | |
| SCHEMBL2343261 | 0.71 | OPRM1 (0.42) | HCAR1ALDH1A1KDM4E | |
| SCHEMBL11006351 | 0.71 | PI4KB (0.53) | L3MBTL1HCAR1GAAALDH1A1TP53 | |
| SCHEMBL2030741 | 0.70 | L3MBTL1 (0.57) | L3MBTL1HPGDGAAALDH1A1TP53 | |
| SCHEMBL21310845 | 0.70 | HCAR1 (0.50) | L3MBTL1HCAR1ALDH1A1TP53PRKACA | |
| SCHEMBL572954 | 0.70 | ALK (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | claimed |