Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117688 | 0.77 | HTR2B (0.44) | TBXAS1SLC6A2SLC6A4 | |
| SCHEMBL11112746 | 0.75 | TBXAS1 (0.43) | TBXAS1SLC6A2SLC6A4 | |
| SCHEMBL11119745 | 0.75 | ALDH1A1 (0.39) | TBXAS1SLC6A2SLC6A4SLC6A3HTT | |
| SCHEMBL11129673 | 0.75 | TBXAS1 (0.38) | TBXAS1SLC6A2SLC6A4 | |
| SCHEMBL11115157 | 0.75 | HTR2B (0.43) | TBXAS1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11113195 | 0.73 | SMPD1 (0.58) | — | |
| SCHEMBL11115708 | 0.72 | GRM7 (0.40) | TBXAS1SLC6A2SLC6A4SLC6A3GRM7 | |
| SCHEMBL11118945 | 0.71 | TBXAS1 (0.39) | TBXAS1SLC6A2SLC6A4 | |
| SCHEMBL11118942 | 0.69 | DRD2 (0.41) | TBXAS1SLC6A2SLC6A4GRM7HTT | |
| SCHEMBL10559305 | 0.68 | DRD2 (0.42) | SLC6A2SLC6A4GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |
| EP-0038564-A1 | Dibenz (b,e) oxepin derivatives and pharmaceutical compositions comprising them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1981-10-28 | — | — | EP | disclosed |