Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115157 | 0.80 | HTR2B (0.43) | TBXAS1SLC6A2SLC6A4DRD2DRD3 | |
| SCHEMBL11119745 | 0.78 | ALDH1A1 (0.39) | TBXAS1SMPD1SLC6A2SLC6A4DRD2 | |
| SCHEMBL11113195 | 0.78 | SMPD1 (0.58) | SMPD1POLBMAPT | |
| SCHEMBL11117688 | 0.77 | HTR2B (0.44) | TBXAS1SLC6A2SLC6A4DRD2DRD3 | |
| SCHEMBL11112746 | 0.76 | TBXAS1 (0.43) | TBXAS1SLC6A2SLC6A4DRD2DRD3 | |
| SCHEMBL11129673 | 0.75 | TBXAS1 (0.38) | TBXAS1SLC6A2SLC6A4DRD2DRD3 | |
| SCHEMBL11155482 | 0.74 | HTR2A (0.40) | TBXAS1SMPD1 | |
| SCHEMBL11111420 | 0.72 | ALOX15 (0.40) | TBXAS1SMPD1SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL11118942 | 0.72 | DRD2 (0.41) | TBXAS1POLBSLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL11113353 | 0.71 | HRH1 (0.41) | TBXAS1MAPTSLC6A2SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |