Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TOP2A | P11388 | 4/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28898260 | 0.99 | KDM4E (0.57) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL22506564 | 0.89 | PIK3CG (0.46) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL30906935 | 0.89 | KDM4E (0.59) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL3815099 | 0.89 | KDM4E (0.59) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL29766836 | 0.84 | KDM4E (0.59) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL13497297 | 0.84 | KDM4E (0.59) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL2744582 | 0.84 | KDM4E (0.59) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL3819912 | 0.84 | KDM4E (0.59) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL9844577 | 0.83 | KDM4E (0.56) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA | |
| SCHEMBL11114605 | 0.83 | PIK3CG (0.42) | KDM4EPIK3CGPIK3CDPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929180-B1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE IND CO LTD (CN) | 2026-03-04 | — | — | EP | disclosed |
| US-20250313533-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2025-10-09 | — | — | US | disclosed |
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| EP-3929180-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shandong United Pesticide Industry Co., Ltd. (CN) | 2021-12-29 | — | — | EP | disclosed |
| EP-3929180-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shandong United Pesticide Industry Co., Ltd. (CN) | 2021-12-29 | — | — | EP | disclosed |
| WO-2020199981-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | 山东省联合农药工业有限公司 | 2020-10-08 | — | — | WO | disclosed |
| WO-2020199981-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | 山东省联合农药工业有限公司 | 2020-10-08 | — | — | WO | disclosed |
| CN-110066245-B | Quinoline carboxylic ester compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-104292159-B | A kind of preparation method of norfloxacin, ciprofloxacin and enrofloxacin | 浙江同丰医药化工有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-103420938-A | Method for recovering piperazine after piperazine condensation reaction in quinolone medicine preparation | ZHEJIANG JINGXIN PHARMACEUTICAL CO LTD | 2013-12-04 | — | — | CN | disclosed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313533-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | NAAA, SDHA, GLUL | KDM4E 858/4885PIK3CG 2795/4885PIK3CD 1993/4885 |
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SDHA, GLUL, PGLS | KDM4E 1227/4885PIK3CG 2675/4885PIK3CD 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.