Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 known ✓ | Q92731 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516528 | 0.97 | TLR8 (0.40) | TLR8MAPTNCEH1GPR84ESR1 | |
| SCHEMBL66353 | 0.97 | TLR8 (0.40) | TLR8MAPTNCEH1GPR84ESR1 | |
| Formaldehyde SCHEMBL18140367 | 0.96 | MAPT (0.40) | TLR8MAPTGPR84KDM4EALDH1A1 | |
| Water SCHEMBL9133681 | 0.96 | TLR8 (0.39) | TLR8MAPTNCEH1GPR84ESR1 | |
| Formaldehyde SCHEMBL18141360 | 0.95 | MAPT (0.42) | TLR8MAPTATMKDM4EALDH1A1 | |
| Formaldehyde SCHEMBL18140651 | 0.95 | MAPT (0.42) | TLR8MAPTATMKDM4EALDH1A1 | |
| Formaldehyde SCHEMBL18140909 | 0.95 | MAPT (0.42) | TLR8MAPTATMKDM4EALDH1A1 | |
| Formaldehyde SCHEMBL18141413 | 0.95 | MAPT (0.42) | TLR8MAPTATMKDM4EALDH1A1 | |
| Formaldehyde SCHEMBL18140794 | 0.95 | MAPT (0.42) | TLR8MAPTATMKDM4EALDH1A1 | |
| Formaldehyde SCHEMBL18141608 | 0.95 | MAPT (0.42) | TLR8MAPTATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109757473-B | Crystallization inhibition composition, application and crystallization inhibition method | 上海生农生化制品股份有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-112841210-A | Dispersing wetting agent composition | 上海生农生化制品股份有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-116814104-A | Preparation method of pseudo-classic repair effect acrylic painting pigment and pigment thereof | 广州市美帮祈富文仪有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116790145-A | Preparation method of high-chroma anti-dry-crack gouache painting pigment and pigment thereof | 广州市美帮祈富文仪有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-115505306-A | Preparation method of acrylic painting pigment with retro repair effect and pigment thereof | 广州市美帮祈富文仪有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115418127-A | Preparation method of high-chroma dry-cracking-resistant gouache painting pigment and pigment thereof | 广州市美帮祈富文仪有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-11406105-B2 | Agrochemical composition and dispersal method therefor | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2022-08-09 | — | — | US | disclosed |
| CN-109757473-B | Crystallization inhibition composition, application and crystallization inhibition method | 上海生农生化制品股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| EP-3384774-B1 | AGROCHEMICAL COMPOSITION AND DISPERSAL METHOD THEREFOR | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2021-07-07 | — | — | EP | disclosed |
| CN-108552183-B | Pyrazolyl cloquintocet-mexyl suspension seed coating agent and application thereof | 河北省农林科学院植物保护研究所 | 2020-12-15 | — | — | CN | disclosed |
| US-20200236943-A1 | AGROCHEMICAL COMPOSITION AND DISPERSAL METHOD THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
| US-10428194-B2 | Modified acrylic resin cured product, and laminate thereof, and production methods therefor | MITSUI CHEMICALS, INC. (JP) | 2019-10-01 | — | — | US | disclosed |
| EP-3263635-B1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | MITSUI CHEMICALS INC (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-20180352813-A1 | AGROCHEMICAL COMPOSITION AND DISPERSAL METHOD THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-3384774-A1 | AGROCHEMICAL COMPOSITION AND DISPERSAL METHOD THEREFOR | Kumiai Chemical Industry Co., Ltd. (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-20180163056-A1 | HYDROPHILIC CURABLE COMPOSITIONS | MITSUI CHEMICALS, INC. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180030230-A1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | MITSUI CHEMICALS, INC. (JP) | 2018-02-01 | — | — | US | disclosed |
| EP-3263635-A1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | Mitsui Chemicals, Inc. (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-3081578-A1 | COMPOSITION FOR HYDROPHILIC CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-0114402-A2 | Method of developing light-sensitive planographic printing plates and automatic development apparatus | FUJI PHOTO FILM CO., LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |