Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119013 | 0.77 | MEN1 (0.38) | OPRM1SCN4ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11114003 | 0.72 | OPRM1 (0.37) | OPRM1SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL11115855 | 0.72 | KDM4E (0.40) | OPRM1 | |
| SCHEMBL11114801 | 0.69 | SCN4A (0.35) | OPRM1SCN4AHTR2C | |
| SCHEMBL11117393 | 0.69 | SCN4A (0.39) | OPRM1SCN4A | |
| SCHEMBL11115188 | 0.69 | SCN4A (0.39) | OPRM1SCN4A | |
| SCHEMBL11117599 | 0.68 | LMNA (0.43) | OPRM1SCN4ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11113533 | 0.68 | HTR1A (0.35) | OPRM1SCN4A | |
| SCHEMBL11115485 | 0.68 | SCN4A (0.34) | OPRM1SCN4A | |
| SCHEMBL11116061 | 0.68 | SCN4A (0.40) | OPRM1SCN4AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |