Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | IDH1 | O75874 | 1/20 | 0.58 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15646419 | 0.78 | MEN1 (0.67) | MEN1KMT2AIDH1MAPTPOLB | |
| SCHEMBL7443125 | 0.77 | SLC25A1 (0.68) | MEN1KMT2AIDH1SLC25A1MAPT | |
| SCHEMBL259390 | 0.75 | MEN1 (0.66) | MEN1KMT2AIDH1MAPTPOLB | |
| SCHEMBL27927882 | 0.74 | POLB (0.63) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL15702526 | 0.73 | IDH1 (1.00) | IDH1 | |
| SCHEMBL12127309 | 0.73 | ALDH1A1 (0.60) | KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7572373 | 0.73 | L3MBTL1 (0.67) | MEN1KMT2AIDH1MAPTPOLB | |
| SCHEMBL8426004 | 0.72 | GAA (0.57) | MEN1KMT2AIDH1MAPTLMNA | |
| SCHEMBL16431026 | 0.72 | PGR (0.64) | MEN1KMT2ASLC25A1POLBALDH1A1 | |
| SCHEMBL8425835 | 0.72 | MEN1 (0.56) | MEN1KMT2ASLC25A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58219159-A | — | — | None | — | — | JP | disclosed |
| JP-S58219159-A | SULFONAMIDE COMPOUND | MITSUI TOATSU CHEM INC | 1983-12-20 | — | — | JP | disclosed |