Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114103 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL8159898 | 0.81 | PABPC1 (0.41) | SMN1; SMN2LMNACTDSP1PABPC1EIF4H | |
| SCHEMBL8153475 | 0.79 | PABPC1 (0.41) | SMN1; SMN2LMNACTDSP1PABPC1EIF4H | |
| SCHEMBL1114157 | 0.75 | PABPC1 (0.42) | SMN1; SMN2LMNACTDSP1PABPC1EIF4H | |
| Tetrabuthylammonium SCHEMBL1113137 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2CTDSP1PABPC1EIF4H | |
| SCHEMBL1114122 | 0.72 | PABPC1 (0.48) | SMN1; SMN2CHRM2CHRM1CHRM3LMNA | |
| Acetoacetic Acid SCHEMBL11104714 | 0.71 | PABPC1 (0.32) | SMN1; SMN2CTDSP1PABPC1EIF4HALDH1A1 | |
| SCHEMBL1111581 | 0.70 | BBOX1 (0.35) | ALDH1A1 | |
| SCHEMBL11015342 | 0.70 | CA2 (0.37) | — | |
| SCHEMBL8773420 | 0.70 | CA12 (0.41) | SMN1; SMN2LMNACTDSP1PABPC1EIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | claimed |
| US-8642778-B2 | Ionic liquids | MERCK PATENT GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-20110152537-A1 | IONIC LIQUIDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-23 | — | — | US | disclosed |
| EP-2279192-A2 | IONIC LIQUIDS | Merck Patent GmbH (DE) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009152902-A2 | IONIC LIQUIDS | MERCK PATENT GMBH, (DE) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152537-A1 | IONIC LIQUIDS | HCN3, CHRNA3, CHRM3 | SMN1; SMN2 1636/4885CHRM2 41/4885CHRM1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.