Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148572 | 0.78 | BTK (0.43) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL11150491 | 0.76 | HSD17B10 (0.41) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11145581 | 0.71 | MEN1 (0.52) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11153753 | 0.69 | MAPT (0.43) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11151333 | 0.68 | MAPT (0.39) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11149542 | 0.66 | PARP14 (0.47) | RAB9AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL11147960 | 0.66 | ALDH1A1 (0.38) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11334717 | 0.66 | THRB (0.44) | ALDH1A1HPGDTHRBHSD17B10KDM4E | |
| SCHEMBL11216887 | 0.64 | ALDH1A1 (0.48) | RAB9ANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL11149698 | 0.64 | EP300 (0.45) | ALDH1A1HPGDHSD17B10KDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |