Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372020 | 0.87 | SMN1; SMN2 (0.43) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL5685882 | 0.86 | MMP12 (0.41) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL5683079 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL11127400 | 0.79 | SMN1; SMN2 (0.36) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL7755523 | 0.77 | ALDH1A1 (0.40) | ALDH1A1ATMTSHRHSD17B10TDP1 | |
| SCHEMBL28303944 | 0.77 | MMP2 (0.43) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL27767604 | 0.77 | GABBR2 (0.43) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL11208829 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL27183172 | 0.77 | ADAMTS4 (0.45) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL3701827 | 0.76 | PSIP1 (0.50) | ALDH1A1MMP1MMP7MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400504-A | DYEING AND PRINTING CELLULOSE AND POLYAMIDE AND-URETHANE FIBERS; TRIAZINE, PYRIDINE AND PYRIMIDINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| EP-0040358-B1 | PROCESS FOR THE PREPARATION OF SULPHONYL CARBOXYLIC ACIDS | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |
| US-4338262-A | INTERMEDIATES FOR PREPARATION OF REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-07-06 | — | — | US | disclosed |
| EP-0053743-A2 | Reactive dioxazine dyestuffs, process for their preparation and their use in dyeing and printing fibrous materials containing hydroxyle or amide groups | BAYER AG (DE) | 1982-06-16 | — | — | EP | disclosed |
| EP-0040358-A1 | Process for the preparation of sulphonyl carboxylic acids | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |