Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625448 | 0.87 | ALDH1A1 (0.41) | ALDH1A1SLC1A3SLC1A2SLC1A1MMP1 | |
| SCHEMBL27560669 | 0.81 | MMP13 (0.44) | ALDH1A1SLC1A3SLC1A2SLC1A1MMP1 | |
| SCHEMBL27853852 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL27183172 | 0.81 | ADAMTS4 (0.45) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL8732760 | 0.78 | CA12 (0.44) | ALDH1A1SLC1A3SLC1A2SLC1A1LARS1 | |
| SCHEMBL2453682 | 0.78 | KEAP1 (0.42) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL11208829 | 0.77 | ALDH1A1 (0.42) | GABBR2GABBR1ALDH1A1MMP1MMP7 | |
| SCHEMBL28303944 | 0.77 | MMP2 (0.43) | ALDH1A1MMP1MMP7MMP12MMP13 | |
| SCHEMBL11147306 | 0.77 | ALDH1A1 (0.42) | GABBR2GABBR1ALDH1A1MMP1MMP7 | |
| Hydrochloric Acid SCHEMBL29141929 | 0.76 | CA12 (0.43) | ALDH1A1SLC1A3SLC1A2SLC1A1LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471260-B | Novel benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-10-22 | — | — | CN | disclosed |
| CN-102471260-A | Novel benzenesulfonamide compounds, process for their synthesis and their use in pharmaceuticals and cosmetics | GALDERMA RES & DEV | 2012-05-23 | — | — | CN | disclosed |
| CN-101472892-A | Organic compounds | NOVARTIS AG (CH) | 2009-07-01 | — | — | CN | disclosed |