Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950761 | 0.84 | HSP90AA1 (0.42) | TSHRHSP90AA1PTGESMAPK1LMNA | |
| SCHEMBL11166612 | 0.81 | HSP90AA1 (0.40) | TSHRHSP90AA1KDM4EPTGESMAPK1 | |
| SCHEMBL10947750 | 0.72 | HSP90AA1 (0.44) | HSP90AA1LMNAHPGDMEN1KMT2A | |
| SCHEMBL19001159 | 0.70 | LMNA (0.53) | TSHRKDM4EPTGESLMNAHPGD | |
| SCHEMBL14085921 | 0.70 | LMNA (0.53) | TSHRKDM4EPTGESLMNAHPGD | |
| SCHEMBL18216887 | 0.70 | LMNA (0.56) | TSHRPTGESLMNAHPGDMEN1 | |
| Benzamide SCHEMBL10949386 | 0.68 | PTGS1 (0.43) | TSHRHSP90AA1TDP1MEN1KMT2A | |
| SCHEMBL18347680 | 0.68 | HPGD (0.43) | TSHRHSP90AA1KDM4EHPGDMEN1 | |
| SCHEMBL11062225 | 0.67 | ERCC1 (0.46) | TSHRHSP90AA1KDM4EMEN1KMT2A | |
| SCHEMBL20454623 | 0.66 | PTGES (0.50) | TSHRPTGESMAPK1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082109-A2 | Substituted 2-hydroxyphenylacetic acids and derivatives of them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |