Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL6836710 | 0.90 | — | — | |
| SCHEMBL651536 | 0.88 | AKR1B10 (0.31) | — | |
| Acrylic Acid SCHEMBL6832817 | 0.75 | — | — | |
| SCHEMBL6836707 | 0.75 | TSHR (0.31) | — | |
| SCHEMBL6474918 | 0.66 | ALDH1A1 (0.32) | — | |
| SCHEMBL1006121 | 0.63 | CYP1A2 (0.32) | — | |
| Maleic Acid SCHEMBL29090331 | 0.57 | TSHR (0.53) | — | |
| Acrylic Acid SCHEMBL31539178 | 0.57 | ARG1 (0.31) | — | |
| Fumaric Acid SCHEMBL930661 | 0.56 | TSHR (0.50) | — | |
| Biphenyl SCHEMBL4308447 | 0.56 | HTT (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033001-B1 | ANAEROBICALLY HARDENING ADHESIVES AND SEALANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-04-13 | — | — | EP | disclosed |