SCHEMBL11209387

SCHEMBL11209387

[CH2]c1cc(OC)c2c(c1)C(C)(C)CC2(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11249363 0.75
SCHEMBL11209443 0.73 ALOX5 (0.34) FTO
SCHEMBL11213073 0.73 LMNA (0.50)
SCHEMBL4469324 0.67 CYP3A4 (0.42) FTO
SCHEMBL9217192 0.66 ACHE (0.42)
SCHEMBL11218909 0.65 RXRA (0.35)
SCHEMBL27054971 0.64 RXRA (0.36)
SCHEMBL22203820 0.64 ACHE (0.36)
SCHEMBL11136773 0.63 CA12 (0.41) FTO
SCHEMBL58988 0.62 ACHE (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002742-B1 STILBENE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THESE STILBENE DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-04-14 EP disclosed