Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249363 | 0.86 | — | — | |
| SCHEMBL11209387 | 0.73 | FTO (0.31) | FTO | |
| SCHEMBL11213073 | 0.72 | LMNA (0.50) | MAPTKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL11215262 | 0.69 | RXRA (0.46) | KMT2AMEN1CYP3A4TSHR | |
| SCHEMBL15241086 | 0.68 | PKM (0.47) | ALOX5MAPTKMT2ACYP1A2CYP2C9 | |
| SCHEMBL8115552 | 0.68 | MAPT (0.56) | MAPTL3MBTL1CYP3A4ACHE | |
| SCHEMBL1613430 | 0.66 | MGAM (0.41) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15417892 | 0.66 | CNR2 (0.40) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3812903 | 0.66 | MAPT (0.39) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4469324 | 0.66 | CYP3A4 (0.42) | ALOX5MAPTFTOKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0002742-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THESE STILBENE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-04-14 | — | — | EP | disclosed |
| US-4193931-A | 7-(INDANYL OR NAPHTHYL)-3-METHYL-OCTA-2,4,6-TRIENE DERIVATIVES, ANTITUMOR | HOFFMANN-LA ROCHE INC. (US) | 1980-03-18 | — | — | US | disclosed |
| EP-0002742-A1 | Stilbene derivatives, their preparation and medicines containing these stilbene derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | disclosed |