Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505366 | 0.80 | ALDH1A1 (0.46) | CRHBPCRHR2HDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL11429495 | 0.79 | MAPT (0.44) | CRHBPCRHR2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11214201 | 0.78 | LMNA (0.47) | MAPTSMN1; SMN2HPGDMAPK1KMT2A | |
| SCHEMBL9411919 | 0.77 | MTNR1A (0.46) | CRHBPCRHR2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11206968 | 0.76 | MTNR1B (0.56) | — | |
| SCHEMBL11247415 | 0.75 | TSHR (0.41) | CRHBPCRHR2SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28160294 | 0.75 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL14491916 | 0.75 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL18499750 | 0.73 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL14368012 | 0.72 | SIGMAR1 (0.52) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025164-B1 | DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-13 | — | — | EP | disclosed |
| EP-0025164-A1 | Disazo compounds, process for their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-18 | — | — | EP | disclosed |