Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21979302 | 0.85 | HTR3E (0.53) | MAPTALDH1A1NPC1GAANPSR1 | |
| SCHEMBL9505366 | 0.81 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11438428 | 0.80 | CRHBP (0.51) | MAPTALDH1A1NPC1GAARAB9A | |
| SCHEMBL11247415 | 0.80 | TSHR (0.41) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL11210194 | 0.79 | CRHBP (0.44) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9411919 | 0.78 | MTNR1A (0.46) | MAPTALDH1A1NPC1NPSR1RAB9A | |
| SCHEMBL11206968 | 0.78 | MTNR1B (0.56) | — | |
| SCHEMBL11214201 | 0.76 | LMNA (0.47) | MAPTALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL11222538 | 0.75 | DHODH (0.44) | — | |
| SCHEMBL11684840 | 0.74 | HTR3E (0.46) | MAPTALDH1A1NPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221709-A | Azo pigments | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |
| US-3988312-A | TETRAKISAZO DYES | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3978038-A | POLYAMIDES, POLYESTERS, POLYURETHANES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |