SCHEMBL5608008

SCHEMBL5608008

CC(C)(c1c(Br)c(Br)c(O)c(Br)c1Br)c1c(Br)c(Br)c(O)c(Br)c1Br.CC(C)(c1c(Cl)c(Cl)c(O)c(Cl)c1Cl)c1c(Cl)c(Cl)c(O)c(Cl)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 3/20 0.36
ALOX15 P16050 2/20 0.36
RECQL P46063 2/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112121 0.84 TSHR (0.50) HIF1ACYP3A4CYP1A2CYP2C9ALDH1A1
SCHEMBL299674 0.84 ALOX15 (0.50) HIF1ACYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL4805327 0.72 TSHR (0.47) HIF1ACYP3A4CYP1A2CYP2C9ALDH1A1
SCHEMBL11234312 0.71 ESR1 (0.48) HIF1ACYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL6855998 0.68
SCHEMBL6551990 0.67 ESR1 (0.48) HIF1ACYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL9155146 0.66 ALDH1A1 (0.38) HIF1ACYP3A4CYP1A2CYP2C9ALDH1A1
SCHEMBL298371 0.66 ALDH1A1 (0.38) HIF1ACYP3A4CYP1A2CYP2C9ALDH1A1
SCHEMBL298363 0.66 MEN1 (0.32) HIF1ACYP2C9ALDH1A1HPGDHSD17B10
SCHEMBL4444597 0.66 HPGD (0.60) HIF1AALDH1A1HPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070293608-A1 POLYCARBONATE COMPOSITIONS AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293608-A1 POLYCARBONATE COMPOSITIONS AND ARTICLES FORMED THEREFROM WEE1, WEE2, ATP5MF HIF1A 1343/4885CYP3A4 2114/4885CYP1A2 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.