SCHEMBL11218946

SCHEMBL11218946

CC(Br)c1ccc2c(c1)C(S(=O)(=O)Cl)c1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4327573 0.78 CA1 (0.41) MEN1POLBKMT2A
SCHEMBL2399978 0.71 ELANE (0.53) MEN1POLBKMT2AATMELANE
SCHEMBL10120020 0.66 KAT6A (0.41) MEN1POLBKMT2AATM
SCHEMBL9475159 0.65 CES2 (0.41) POLBKMT2A
SCHEMBL17308141 0.63 GPR3 (0.43) MEN1POLBKMT2A
SCHEMBL30990675 0.62 ALDH1A1 (0.43)
SCHEMBL4586061 0.62 HTR7 (0.43) MEN1POLBKMT2AATM
SCHEMBL10426492 0.62 S100A4 (0.44)
SCHEMBL119251 0.61 UGT2B7 (0.63) MEN1KMT2AATM
SCHEMBL29756087 0.61 UGT2B7 (0.63) MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed