Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904265 | 0.98 | ALDH1A1 (0.42) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL229142 | 0.98 | ALDH1A1 (0.42) | ALDH1A1KDM4ECA12CA1CA2 | |
| Water SCHEMBL4269781 | 0.96 | ALDH1A1 (0.41) | ALDH1A1KDM4ECA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL934319 | 0.96 | ALDH1A1 (0.41) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL29552462 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL3717130 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL14894927 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4ECA12CA1CA2 | |
| Potassium Ion SCHEMBL366682 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL3365753 | 0.94 | ALDH1A1 (0.42) | ALDH1A1KDM4ECA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL23532725 | 0.92 | ALDH1A1 (0.41) | ALDH1A1KDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3705582-B1 | COMPOSITIONS AND METHODS FOR DNA AND RNA EXTRACTION FROM TISSUE SAMPLES | CEPHEID (US) | 2025-09-03 | — | — | EP | claimed |
| CN-120041382-A | In vitro embryo culture solution and preparation method thereof | 河北品元生物科技有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-118425538-A | Abnormal value coagulation seven-item composite quality control product and preparation method thereof | 郑州标源生物科技有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-117721172-A | Application of auxiliary materials and/or nano enzyme in automatic on-line monitoring instrument feeding | 吉林市光大分析技术有限责任公司 | 2024-03-19 | — | — | CN | claimed |
| CN-113861254-B | Tumor PET imaging agent 68 Ga-NOTAN-aDG, and preparation method and application thereof | 复旦大学附属中山医院 | 2023-10-27 | — | — | CN | claimed |
| CN-111686815-B | Self-assembled nano material and preparation method and application thereof | 北京化工大学 | 2023-07-14 | — | — | CN | claimed |
| CN-112831599-B | CoVID-19 virus detection kit based on signal amplification technology | 郑州科蒂亚生物技术有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-109943665-B | Probe sequence for detecting head and neck squamous carcinoma oncogene, kit and application thereof | 郑州科蒂亚生物技术有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-108124451-B | Compositions and methods for extracting DNA and RNA from tissue samples | 塞弗德公司 | 2022-09-09 | — | — | CN | claimed |
| CN-111289424-B | Method for detecting sperm mitochondrial membrane potential and active oxygen by double-standard method | 浙江星博生物科技股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-110508322-B | Self-assembly nano material and preparation method and application thereof | 国家纳米科学中心 | 2022-04-12 | — | — | CN | claimed |
| EP-2721391-B1 | SOLUTION AND METHOD FOR HISTOPROCESSING OF BIOLOGICAL SAMPLES | ROCHE DIAGNOSTICS HEMATOLOGY INC (US) | 2022-04-06 | — | — | EP | claimed |
| CN-106686977-B | PH adjustment to improve thawing recovery of cell banks | 豪夫迈·罗氏有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-119978403-B | Coordination polymer based on pesticide ligand, preparation method and application thereof | 北京农学院 | 2026-05-19 | — | — | CN | disclosed |
| CN-122012423-A | Method for crystallizing BM3 protein in bacillus megatherium | 安徽大学 | 2026-05-12 | — | — | CN | disclosed |
| US-20260124203-A1 | CHEMICAL SYNTHETIC LETHALITY FOR ANTIMICROBIAL THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2026-05-07 | — | — | US | disclosed |
| EP-0656349-A1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |
| EP-0301182-B1 | Reagent for reticulocyte counting by flow cytometry | TOA MEDICAL ELECTRONICS (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |
| EP-0301182-A2 | Reagent for reticulocyte counting by flow cytometry | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1989-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124203-A1 | CHEMICAL SYNTHETIC LETHALITY FOR ANTIMICROBIAL THERAPY | COASY, GLO1, FARS2 | CHRM2 4405/4885CHRM1 4583/4885MEN1 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.