Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.45 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6603171 | 1.00 | TDP1 (0.54) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| SCHEMBL1122017 | 0.98 | TDP1 (0.55) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| SCHEMBL31255200 | 0.98 | TDP1 (0.55) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| SCHEMBL3771280 | 0.89 | TDP1 (0.52) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| Acetic Acid SCHEMBL4444086 | 0.88 | KMT2A (0.53) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| SCHEMBL3926418 | 0.87 | TDP1 (0.51) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6157878 | 0.86 | TDP1 (0.56) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL637924 | 0.86 | TDP1 (0.56) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL16165936 | 0.86 | TDP1 (0.56) | TDP1L3MBTL1KMT2AALDH1A1HTT | |
| Hydrazine SCHEMBL3964002 | 0.86 | TDP1 (0.50) | TDP1L3MBTL1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812423-A | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine and hydrochloride thereof | 南通泰禾化工股份有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-117417293-B | Synthesis method of fluopyram | 齐鲁晟华制药有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117417293-A | Synthesis method of fluopyram | 齐鲁晟华制药有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-116836110-A | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride | 天津均凯农业科技有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116836110-B | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride | 天津均凯农业科技有限公司 | 2026-02-10 | — | — | CN | disclosed |
| CN-116836110-B | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride | 天津均凯农业科技有限公司 | 2026-02-10 | — | — | CN | disclosed |
| CN-119684204-A | Preparation method of fluopyram intermediate | 顺毅南通化工有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119462491-A | Fluopicola strain method for synthesizing amide | 南通泰禾化工股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-118851992-A | Fluopicola strain method for synthesizing amide | 江苏海洋大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118812423-A | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine and hydrochloride thereof | 南通泰禾化工股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118812423-A | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine and hydrochloride thereof | 南通泰禾化工股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118206527-A | N-pyridine ethyl pyrimidine amine compound | 湖南化工研究院有限公司 | 2024-06-18 | — | — | CN | disclosed |
| EP-1597252-B1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | BAYER SAS (FR) | 2011-02-09 | — | — | EP | disclosed |
| US-7754741-B2 | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE S.A. (FR) | 2010-07-13 | — | — | US | disclosed |
| CN-100402525-C | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE SA (FR) | 2008-07-16 | — | — | CN | disclosed |
| CN-1751039-A | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE SA (FR) | 2006-03-22 | — | — | CN | disclosed |
| US-20060052366-A1 | Pyridine derivatives as fungicidal compounds | BAYER SAS (FR) | 2006-03-09 | — | — | US | disclosed |
| EP-1597252-A1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | Bayer CropScience S.A. (FR) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004074280-A1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | BAYER CROPSCIENCE SA (FR) | 2004-09-02 | — | — | WO | disclosed |
| EP-1449841-A1 | New fungicidal compounds | Bayer CropScience SA (FR) | 2004-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052366-A1 | Pyridine derivatives as fungicidal compounds | CYP3A7, CYP4B1, CYP4X1 | GLA 695/4885GAA 80/4885TDP1 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.