Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 8/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973060 | 0.87 | PDE4A (0.35) | S1PR1XIAPGRIN1GRIN2B | |
| SCHEMBL11191930 | 0.74 | MAOB (0.38) | S1PR1BCHEACHEMAOBMAOA | |
| SCHEMBL11175220 | 0.74 | MAOB (0.38) | S1PR1BCHEACHEMAOBMAOA | |
| SCHEMBL10976470 | 0.74 | HTR1A (0.30) | — | |
| SCHEMBL10472693 | 0.73 | BCHE (0.35) | S1PR1BCHEACHEMAOBMAOA | |
| SCHEMBL10473628 | 0.72 | NAAA (0.35) | S1PR1BCHEACHEMAOBEGFR | |
| SCHEMBL11183533 | 0.69 | PDE4A (0.37) | S1PR1MAOBGRIN1GRIN2BMAOA | |
| SCHEMBL10472686 | 0.69 | ACHE (0.41) | BCHEACHEXIAPMAOBEGFR | |
| SCHEMBL10473638 | 0.67 | ACHE (0.43) | BCHEACHEMAOBMAOA | |
| SCHEMBL10473371 | 0.67 | ACHE (0.43) | BCHEACHEMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351833-A | 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4309545-A | ANALGESICS, TRANQUILIZERS, ANTIEMETICS, DIURETICS, ANTICONVULSANTS, ANTIDIARRHEAL, ANTITUSSIVES AND IN THE TREATMENT OF GLAUCOMA | PFIZER INC. (US) | 1982-01-05 | — | — | US | disclosed |