Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 3/20 | 0.37 |
| ▸ | WNT3 | P56703 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237927 | 0.83 | CYP3A4 (0.37) | SMN1; SMN2MAPTHTTHSD17B10LMNA | |
| SCHEMBL10167002 | 0.76 | ESR1 (0.42) | SMN1; SMN2MAPTHSD17B10SFRP1WNT3 | |
| SCHEMBL10167004 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTSFRP1WNT3ALDH1A1 | |
| SCHEMBL27841266 | 0.68 | ALDH1A1 (0.63) | SMN1; SMN2MAPTHTTSFRP1WNT3 | |
| SCHEMBL3954806 | 0.65 | PTGS2 (0.43) | RORC | |
| SCHEMBL4618478 | 0.65 | SFRP1 (0.55) | SFRP1WNT3 | |
| SCHEMBL7236719 | 0.65 | ESR1 (0.52) | RORC | |
| SCHEMBL19199355 | 0.64 | PIN1 (0.47) | CHRM2CHRM1SMN1; SMN2MAPTHTT | |
| SCHEMBL19199769 | 0.64 | PIN1 (0.47) | CHRM2CHRM1SMN1; SMN2MAPTHTT | |
| SCHEMBL4201103 | 0.64 | HTR6 (0.48) | SMN1; SMN2MAPTSFRP1WNT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349378-A | Compounds useful as pesticides | FBC LIMITED (GB) | 1982-09-14 | — | — | US | disclosed |
| US-4309559-A | PLANT GROWTH REGULATORS AND ESPECIALLY FUNGICIDES OR HERBICIDES | FBC LIMITED (GB) | 1982-01-05 | — | — | US | disclosed |