Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237473 | 0.80 | ALDH1A1 (0.45) | MLYCDKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11239919 | 0.76 | SMN1; SMN2 (0.44) | HTTKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11223677 | 0.75 | EGFR (0.34) | MLYCDGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11223682 | 0.74 | KMT2A (0.35) | MLYCDMEN1KMT2APOLBSMN1; SMN2 | |
| Water SCHEMBL11229478 | 0.74 | MLYCD (0.38) | MLYCDGAAHTTPOLBSMN1; SMN2 | |
| Water SCHEMBL11229473 | 0.74 | MLYCD (0.38) | MLYCDGAAHTTPOLBSMN1; SMN2 | |
| SCHEMBL11236241 | 0.73 | NOTUM (0.44) | MLYCDMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL11227132 | 0.72 | RXRA (0.40) | MLYCDGAAMEN1KMT2A | |
| SCHEMBL11229091 | 0.72 | LMNA (0.34) | MLYCDGAAMEN1KMT2APOLB | |
| SCHEMBL11228961 | 0.71 | TGM2 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |