Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239919 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1KMT2ANOTUMPOLBSMN1; SMN2 | |
| SCHEMBL11229471 | 0.80 | MLYCD (0.36) | ALDH1A1KMT2AMLYCDPOLBSMN1; SMN2 | |
| SCHEMBL11236241 | 0.77 | NOTUM (0.44) | CYP3A4KMT2AMLYCDROCK2NOTUM | |
| SCHEMBL11229091 | 0.77 | LMNA (0.34) | ALDH1A1KMT2AMLYCDPOLB | |
| SCHEMBL11228961 | 0.76 | TGM2 (0.39) | ROCK2NOTUMSMN1; SMN2 | |
| SCHEMBL11223682 | 0.76 | KMT2A (0.35) | KMT2AMLYCDROCK2NOTUMPOLB | |
| SCHEMBL11229271 | 0.75 | NR1H3 (0.49) | ALDH1A1CYP3A4KMT2A | |
| SCHEMBL11236806 | 0.74 | FOLH1 (0.33) | ALDH1A1KMT2AMLYCDPOLBSMN1; SMN2 | |
| SCHEMBL11223677 | 0.74 | EGFR (0.34) | ALDH1A1CYP3A4KMT2AMLYCDROCK2 | |
| SCHEMBL11227132 | 0.74 | RXRA (0.40) | KMT2AMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |