Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232306 | 0.89 | KMT2A (0.40) | MAPTLMNATP53PTGS2GAA | |
| SCHEMBL11252783 | 0.73 | PTGS2 (0.39) | MAPTLMNATP53PTGS2SMN1; SMN2 | |
| SCHEMBL11263728 | 0.72 | ALDH1A1 (0.37) | MAPTLMNATHRBPTGS2GAA | |
| SCHEMBL11233332 | 0.70 | ADRA1A (0.61) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL11255922 | 0.67 | ALDH1A1 (0.37) | MAPTALDH1A1 | |
| SCHEMBL11267568 | 0.65 | HTR2C (0.39) | GAA | |
| SCHEMBL10574941 | 0.62 | FLT1 (0.47) | MAPTHTTPTGS2FLT1FLT4 | |
| SCHEMBL31531993 | 0.61 | FLT1 (0.50) | MAPTLMNATHRBPTGS2SMN1; SMN2 | |
| SCHEMBL3386873 | 0.61 | FLT1 (0.50) | MAPTLMNATHRBPTGS2SMN1; SMN2 | |
| SCHEMBL11267634 | 0.60 | ALDH1A1 (0.43) | MAPTHTTLMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343810-A | Method of inhibiting sickling of sickle erythrocytes using 2-((haloanilino)methyl)-2-imidazolines | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |