Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233336 | 0.89 | MAPT (0.41) | KMT2ALMNAADRA2CMAPTALDH1A1 | |
| SCHEMBL11252783 | 0.74 | PTGS2 (0.39) | KMT2ALMNAMAPTALDH1A1TP53 | |
| SCHEMBL11263728 | 0.73 | ALDH1A1 (0.37) | KMT2ALMNAPKMCA1CA2 | |
| SCHEMBL11232303 | 0.68 | ADRA2C (0.68) | ADRA2BADRA2C | |
| SCHEMBL11255922 | 0.68 | ALDH1A1 (0.37) | MAPTALDH1A1 | |
| SCHEMBL11267568 | 0.67 | HTR2C (0.39) | GAA | |
| SCHEMBL11180678 | 0.67 | ADRA2B (0.46) | KMT2ALMNAADRA2BADRA2CMAPT | |
| SCHEMBL11473474 | 0.65 | FAAH (0.43) | KMT2ALMNAPKMADRA2BADRA2C | |
| SCHEMBL11180683 | 0.64 | ADRA2B (0.46) | KMT2ALMNAADRA2BADRA2CMAPT | |
| SCHEMBL3386873 | 0.62 | FLT1 (0.50) | KMT2ALMNAPKMCA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343810-A | Method of inhibiting sickling of sickle erythrocytes using 2-((haloanilino)methyl)-2-imidazolines | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |