Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LDLR | P01130 | 3/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24283555 | 0.79 | GRN (0.70) | CTSLCTSKCTSBCTSSGRN | |
| SCHEMBL24997896 | 0.77 | RECQL (0.51) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL5720786 | 0.77 | BDKRB2 (0.52) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL5521614 | 0.76 | CTSL (0.83) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7539158 | 0.76 | CTSL (0.55) | CTSLCTSKCTSBCTSSGRN | |
| SCHEMBL15204487 | 0.75 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHTTRAB9A | |
| SCHEMBL14452805 | 0.75 | HTR4 (0.48) | CTSLCTSKCTSSALDH1A1MEN1 | |
| SCHEMBL8389571 | 0.74 | HDAC6 (0.68) | HDAC3HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL163588 | 0.74 | MLYCD (0.61) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL13754271 | 0.74 | RAB9A (0.64) | CTSLCTSKCTSBCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |