Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226881 | 0.78 | HTR6 (0.46) | HTR6APP | |
| Hydrochloric Acid SCHEMBL11226281 | 0.77 | HTR6 (0.46) | HTR6APP | |
| SCHEMBL11220044 | 0.76 | DRD2 (0.57) | HTR6DRD2 | |
| SCHEMBL9312433 | 0.74 | ALDH1A1 (0.43) | SIGMAR1 | |
| SCHEMBL10640414 | 0.72 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL11405505 | 0.72 | KDM4E (0.56) | BCHESIGMAR1 | |
| Oxalic Acid SCHEMBL11227420 | 0.71 | MAPK14 (0.53) | SIGMAR1DRD2 | |
| SCHEMBL11226335 | 0.70 | CHRM2 (0.39) | SIGMAR1DRD2 | |
| SCHEMBL2783395 | 0.70 | HTR1A (0.66) | DRD2 | |
| SCHEMBL31530785 | 0.70 | HTR1A (0.66) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | disclosed |