SCHEMBL1123535

SCHEMBL1123535

C#CCc1c(I)cccc1NC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2D6 P10635 3/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP3A4 P08684 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8590878 0.79 MEN1 (0.33) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL77844 0.79 ALDH1A1 (0.41) MEN1KMT2ALMNATDP1POLB
SCHEMBL5960886 0.76 NPC1 (0.39) NPC1RAB9AHPGDPOLBKCNK3
SCHEMBL8593060 0.76 RAB9A (0.32) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL3963323 0.75 POLB (0.41) CYP2C19TDP1POLB
SCHEMBL3962321 0.73 POLB (0.42) POLBKCNK3KCNK9
SCHEMBL2092377 0.72 GRIK1 (0.50) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL1901409 0.68 MEN1 (0.36) MEN1KMT2A
SCHEMBL18138901 0.67 MAPT (0.51) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL17220695 0.67 AKR1B1 (0.48) MEN1KMT2ACYP1A2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215572-A1 ANTIMICROBIAL PARTICLE DISPERSION MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2024-07-04 US claimed
EP-1981629-B1 IPBC-CONTAINING COACERVATES LANXESS DEUTSCHLAND GMBH (DE) 2013-10-16 EP claimed
US-7083801-B2 Stabilized haloalkynyl microbicide compositions ROHM AND HAAS COMPANY 2006-08-01 US claimed
EP-1382248-B1 Stabilized haloalkynyl microbicide compositions ROHM & HAAS (US) 2005-10-05 EP claimed
US-20040014736-A1 Stabililzed haloalkynyl microbicide compositions ROHM AND HAAS COMPANY 2004-01-22 US claimed
EP-1382248-A1 Stabilized haloalkynyl microbicide compositions ROHM AND HAAS COMPANY (US) 2004-01-21 EP claimed
EP-1164850-B1 AQUEOUS FUNGICIDE DISPERSION AVECIA LTD (GB) 2003-06-25 EP claimed
US-6506794-B1 An aqueous dispersion comprising a halopropargyl compound and a partially hydrolysed polyvinyl alcohol. The aqueous dispersions are useful for inhibiting the growth of micro-organisms on or in a medium, especially an industrial AVECIA INC. 2003-01-14 US claimed
EP-1164850-A1 AQUEOUS FUNGICIDE DISPERSION Avecia Limited (GB) 2002-01-02 EP claimed
WO-2000057702-A1 AQUEOUS FUNGICIDE DISPERSION AVECIA LIMITED (GB) 2000-10-05 WO claimed
JP-2231404-A None JP disclosed
EP-4692252-A1 FUNCTIONAL PARTICLE DISPERSION MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2026-02-11 EP disclosed
EP-3663366-B1 USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS SYMRISE AG (DE) 2025-01-08 EP disclosed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP disclosed
US-20240215572-A1 ANTIMICROBIAL PARTICLE DISPERSION MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2024-07-04 US disclosed
WO-2000057702-A1 AQUEOUS FUNGICIDE DISPERSION AVECIA LIMITED (GB) 2000-10-05 WO disclosed
US-5773157-A SUBSTRATE WITH MAGNETIC COATING LAYER OF POWDERS AND BINDERS TEIJIN LIMITED (JP) 1998-06-30 US disclosed
EP-0640959-B1 Magnetic recording medium with fungiresistance and process for manufacturing same TEIJIN LTD (JP) 1998-01-07 EP disclosed
EP-0640959-A1 Magnetic recording medium with fungiresistance and process for manufacturing same TEIJIN LIMITED (JP) 1995-03-01 EP disclosed
JP-H02231404-A WOOD PRESERVATIVE AND SOIL-TREATING AGENT TROY CHEM CORP 1990-09-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240215572-A1 ANTIMICROBIAL PARTICLE DISPERSION Q6ZSR9, PAM, ACMSD MEN1 3614/4885KMT2A 3828/4885NPC1 2204/4885
US-20040014736-A1 Stabililzed haloalkynyl microbicide compositions MGLL, HDHD5, SLC39A14 MEN1 3644/4885KMT2A 2291/4885NPC1 2167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.