Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP10 | P09238 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11242341 | 0.99 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR1ASIGMAR1 | |
| SCHEMBL11248097 | 0.92 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR1ASIGMAR1 | |
| Bromide SCHEMBL11249246 | 0.91 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR1ASIGMAR1 | |
| SCHEMBL11255005 | 0.83 | SCN1A (0.41) | SLC6A2SLC6A4SLC6A3HTR1ASIGMAR1 | |
| SCHEMBL11239680 | 0.82 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR1ASIGMAR1 | |
| SCHEMBL11241295 | 0.81 | USP2 (0.40) | SLC6A2SLC6A4SLC6A3HTR1AALDH1A1 | |
| Bromide SCHEMBL11471759 | 0.81 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1ASIGMAR1 | |
| SCHEMBL11249100 | 0.78 | HTR1A (0.43) | HTR1ASIGMAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL27626859 | 0.77 | SIGMAR1 (0.39) | SLC6A2SLC6A4SLC6A3SIGMAR1MMP3 | |
| Bromide SCHEMBL11248578 | 0.77 | HTR1A (0.43) | HTR1ASIGMAR1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016261-B1 | SPIRO(DIBENZ(B,F)OXEPIN-PIPERIDINES) AND METHODS OF PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |