SCHEMBL11255005

SCHEMBL11255005

CN1CCC(OC(=O)O)(c2ccccc2Oc2ccc(F)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 2/20 0.41
SCN2A Q99250 2/20 0.41
SCN3A Q9NY46 2/20 0.41
RECQL P46063 1/20 0.39
OPRM1 P35372 2/20 0.39
SIGMAR1 Q99720 1/20 0.39
HRH4 Q9H3N8 1/20 0.38
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 1/20 0.38
HTR1A P08908 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SCN9A Q15858 1/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11246085 0.89 MMP1 (0.43) SCN1ASCN2ASCN3ARECQLOPRM1
SCHEMBL11241295 0.88 USP2 (0.40) ALDH1A1HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL11255002 0.83 OPRM1 (0.45) SCN1ASCN2ASCN3ARECQLOPRM1
SCHEMBL11239682 0.83 SLC6A2 (0.44) SIGMAR1ALDH1A1L3MBTL1HTR1ASLC6A2
Bromide SCHEMBL11242341 0.82 SLC6A2 (0.43) SIGMAR1ALDH1A1L3MBTL1HTR1ASLC6A2
SCHEMBL11243000 0.81 USP2 (0.43) ALDH1A1HPGDMAPT
SCHEMBL11248413 0.79 SLC6A9 (0.43) SCN1ASCN2ASCN3AOPRM1ALDH1A1
SCHEMBL11248097 0.75 SLC6A2 (0.41) OPRM1SIGMAR1HTR1ASLC6A2SLC6A4
SCHEMBL11254246 0.74 OPRM1 (0.46) OPRM1HRH4ALDH1A1HTR1ASLC6A2
Bromide SCHEMBL11249246 0.74 SLC6A2 (0.40) OPRM1SIGMAR1HTR1ASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55079367-A None JP disclosed
WO-2024105603-A1 A RUTHENIUM (II) POLYPYRIDYL COMPLEX AS A PHOTO-SENSITISER IN PHOTODYNAMIC THERAPY, AND A PROCEDURE FOR MAKING SAID RUTHENIUM (II) POLYPYRIDYL COMPLEX UNIVERSITÀ DEGLI STUDI DI FIRENZE (IT) 2024-05-23 WO disclosed
WO-2016016413-A1 SYNTHESIS OF A CYCLIC, BRANCHED UNSATURATED COMPOUND BY CROSS METATHESIS ARKEMA FRANCE (FR) 2016-02-04 WO disclosed
EP-0016261-B1 SPIRO(DIBENZ(B,F)OXEPIN-PIPERIDINES) AND METHODS OF PREPARING SAME HOECHST AKTIENGESELLSCHAFT (DE) 1982-12-29 EP disclosed
EP-0016261-A1 Spiro(dibenz(b,f)oxepin-piperidines) and methods of preparing same HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-01 EP disclosed
JP-S5579367-A PYRIDINE COMPOUND, ITS PREPARATION, AND FUNGICIDE COMPRISING IT SUMITOMO CHEM CO LTD 1980-06-14 JP disclosed