Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149109 | 0.80 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL11149158 | 0.80 | MC4R (0.42) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL11165081 | 0.80 | CYP2D6 (0.50) | MEN1KMT2ATSHR | |
| SCHEMBL11155793 | 0.78 | DRD2 (0.45) | MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL11154795 | 0.77 | DRD2 (0.40) | MEN1KMT2AOPRL1 | |
| SCHEMBL11155212 | 0.76 | OPRM1 (0.51) | MEN1KMT2AALDH1A1OPRM1OPRL1 | |
| SCHEMBL11151306 | 0.76 | OPRL1 (0.54) | MEN1KMT2AGAAALDH1A1OPRM1 | |
| SCHEMBL11266008 | 0.74 | DRD2 (0.37) | MEN1KMT2AGAAALDH1A1OPRL1 | |
| SCHEMBL11150812 | 0.71 | RAB9A (0.41) | KMT2AGAAOPRM1LMNAMAPT | |
| SCHEMBL11153010 | 0.71 | CYP2D6 (0.44) | MEN1KMT2AKDM4EOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333942-A | Anti-depressant and analgesic 4-phenoxypiperidines | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-08 | — | — | US | disclosed |