Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 14/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 14/20 | 0.48 |
| ▸ | SGK1 | O00141 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.45 |
| ▸ | DMPK | Q09013 | 1/20 | 0.45 |
| ▸ | MYLK | Q15746 | 1/20 | 0.45 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.45 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 1/20 | 0.44 |
| ▸ | ATP4B | P51164 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607745 | 0.85 | ROCK2 (0.56) | KDM4EALDH1A1MAPTROCK2ROCK1 | |
| Oxalic Acid SCHEMBL11247631 | 0.84 | SIRT5 (0.55) | KDM4EALDH1A1MAPTRAB9AABL1 | |
| SCHEMBL3616071 | 0.83 | PRMT6 (0.62) | KDM4EALDH1A1MAPTROCK2ROCK1 | |
| SCHEMBL11244712 | 0.79 | PRMT6 (0.45) | ROCK2ROCK1SGK1AKT1GSK3B | |
| SCHEMBL11244710 | 0.79 | PRMT6 (0.45) | ROCK2ROCK1SGK1AKT1GSK3B | |
| SCHEMBL8648287 | 0.79 | ROCK2 (0.56) | KDM4EALDH1A1MAPTROCK2ROCK1 | |
| SCHEMBL3613000 | 0.79 | ABL1 (0.54) | KDM4EALDH1A1MAPTROCK1ELOVL1 | |
| SCHEMBL11248010 | 0.79 | SIRT5 (0.52) | KDM4EALDH1A1MAPTRAB9AABL1 | |
| SCHEMBL2395281 | 0.77 | ATP4A (0.49) | ALDH1A1ROCK2ROCK1ELOVL1RAB9A | |
| SCHEMBL3609767 | 0.76 | PHGDH (0.55) | ALDH1A1MAPTROCK1RAB9AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003640-B1 | ANTISECRETORY GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-01-27 | — | — | EP | disclosed |