Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249700 | 0.81 | HTR2B (0.47) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| SCHEMBL7291902 | 0.79 | AKR1B1 (0.42) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| Hydrochloric Acid SCHEMBL11256890 | 0.76 | ADRA2A (0.45) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| SCHEMBL11247633 | 0.72 | ALDH1A1 (0.48) | LMNAMEN1KMT2APOLBCYP1A2 | |
| SCHEMBL8668407 | 0.69 | HTR2B (0.55) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| SCHEMBL11249009 | 0.69 | CYP1A2 (0.39) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| Hydrochloric Acid SCHEMBL7942184 | 0.68 | ADRA2A (0.56) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| SCHEMBL8830155 | 0.67 | ALDH1A1 (0.41) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| SCHEMBL11040309 | 0.67 | ALDH1A1 (0.41) | ADRA2AHTR2BLMNACYP2D6HIF1A | |
| SCHEMBL6260569 | 0.66 | CXCL8 (0.53) | ADRA2AHTR2BLMNACYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318915-A | Substituted guandines and methods of preparation thereof | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |