Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260619 | 0.87 | MAOA (0.34) | OPRM1CTSKCTSLCTSBOPRL1 | |
| SCHEMBL11261166 | 0.84 | MEN1 (0.34) | OPRM1CTSKCTSLCTSBMMP9 | |
| SCHEMBL11266397 | 0.81 | MAOA (0.36) | OPRM1OPRL1MAOAMAOBAPOBEC3A | |
| SCHEMBL11155212 | 0.74 | OPRM1 (0.51) | OPRM1OPRL1 | |
| SCHEMBL11155793 | 0.70 | DRD2 (0.45) | OPRM1OPRL1 | |
| SCHEMBL11149109 | 0.70 | KDM4E (0.47) | OPRM1OPRL1 | |
| SCHEMBL11149158 | 0.69 | MC4R (0.42) | OPRM1LTA4HOPRL1MAOAMAOB | |
| SCHEMBL11153360 | 0.68 | TACR1 (0.43) | OPRM1MAOAMAOB | |
| SCHEMBL6933387 | 0.67 | MMP2 (0.43) | OPRM1LTA4HOPRL1MMP2MMP9 | |
| SCHEMBL3880114 | 0.67 | MMP2 (0.43) | OPRM1LTA4HOPRL1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333942-A | Anti-depressant and analgesic 4-phenoxypiperidines | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-08 | — | — | US | disclosed |