Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 2/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249863 | 0.84 | OPRM1 (0.36) | OPRM1MMP9MAOAMAOBCTSL | |
| SCHEMBL11260619 | 0.83 | MAOA (0.34) | MEN1KMT2AOPRM1MAOAMAOB | |
| SCHEMBL11266397 | 0.80 | MAOA (0.36) | MEN1KMT2AOPRM1MAOAMAOB | |
| SCHEMBL11154795 | 0.74 | DRD2 (0.40) | MEN1KMT2A | |
| SCHEMBL11165081 | 0.71 | CYP2D6 (0.50) | MEN1KMT2A | |
| SCHEMBL11149158 | 0.68 | MC4R (0.42) | MEN1KMT2AOPRM1MAOAMAOB | |
| SCHEMBL11247084 | 0.68 | MEN1 (0.52) | MEN1KMT2AOPRM1 | |
| SCHEMBL11153360 | 0.68 | TACR1 (0.43) | MEN1KMT2AOPRM1MAOAMAOB | |
| SCHEMBL11149109 | 0.66 | KDM4E (0.47) | MEN1KMT2AOPRM1 | |
| SCHEMBL11151306 | 0.64 | OPRL1 (0.54) | MEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333942-A | Anti-depressant and analgesic 4-phenoxypiperidines | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-08 | — | — | US | disclosed |