Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126919 | 0.83 | HTR3E (0.52) | KDM4EALDH1A1CHEK1KMT2AF2 | |
| SCHEMBL943023 | 0.79 | MAPT (0.55) | MAPTKDM4ELMNAGFERTSHR | |
| SCHEMBL942722 | 0.76 | MAPT (0.51) | MAPTKDM4ELMNAGFERTSHR | |
| SCHEMBL1126421 | 0.74 | ALDH1A1 (0.48) | MAPTKDM4ELMNAALDH1A1TDP1 | |
| SCHEMBL942805 | 0.74 | SIRT6 (0.56) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL942660 | 0.73 | GAA (0.55) | MAPTKDM4ELMNAGFERTSHR | |
| SCHEMBL28319150 | 0.72 | NPC1 (0.58) | MAPTKDM4ELMNATSHRMAPK1 | |
| SCHEMBL1645844 | 0.71 | MAPT (0.56) | MAPTKDM4ELMNAGFERTSHR | |
| SCHEMBL1127038 | 0.71 | PHGDH (0.47) | MAPTKDM4ELMNAGFERTSHR | |
| SCHEMBL1019837 | 0.71 | MAPT (0.46) | MAPTKDM4ELMNAGFERTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |