SCHEMBL1126803

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126957	0.86	ALDH1A1 (0.50)	ALDH1A1KDM4EPOLBL3MBTL1TSHR
	SCHEMBL1126785	0.77	ALDH1A1 (0.49)	ALDH1A1KDM4EPOLBL3MBTL1TSHR
	SCHEMBL28850677	0.76	ALDH1A1 (0.53)	ALDH1A1KDM4EPOLBL3MBTL1MAPT
	SCHEMBL32675941	0.75	ALDH1A1 (0.47)	ALDH1A1KDM4EPOLBL3MBTL1MAPT
	SCHEMBL1127178	0.73	CNR1 (0.44)	ALDH1A1KDM4EPOLBL3MBTL1LMNA
	SCHEMBL1126880	0.73	CNR2 (0.48)	ALDH1A1KDM4EPOLBTSHRHTT
	SCHEMBL1126874	0.71	CA12 (0.52)	ALDH1A1KDM4EPOLBL3MBTL1TSHR
	SCHEMBL1126573	0.71	ALDH1A1 (0.49)	ALDH1A1KDM4EPOLBTSHRMAPT
	SCHEMBL14947704	0.71	NTSR1 (0.57)	ALDH1A1KDM4EPOLBL3MBTL1TSHR
	SCHEMBL1126744	0.71	ALDH1A1 (0.45)	ALDH1A1KDM4ETSHRHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.