Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126618 | 0.84 | EGFR (0.40) | HPGDMAPK1CYP1A2CYP2C19TP53 | |
| SCHEMBL1126776 | 0.72 | ALDH1A1 (0.53) | ALDH1A1ALOX5HPGDMAPTMAPK1 | |
| SCHEMBL1126638 | 0.70 | CLEC4M (0.43) | JAK2JAK3CYP1A2CYP2C19PDE3B | |
| SCHEMBL1990531 | 0.70 | JAK2 (0.53) | JAK2JAK3ALDH1A1ALOX5HPGD | |
| SCHEMBL30741062 | 0.69 | JAK2 (0.52) | JAK2JAK3ALDH1A1ALOX5HPGD | |
| SCHEMBL15162603 | 0.69 | GABRA2 (0.45) | JAK2JAK3ALOX5MAPTTRPM8 | |
| SCHEMBL20806415 | 0.69 | CYP1A2 (0.53) | JAK2JAK3ALDH1A1ALOX5HPGD | |
| SCHEMBL5988350 | 0.68 | TRPM8 (0.46) | JAK2JAK3ALDH1A1ALOX5MAPT | |
| SCHEMBL12991545 | 0.68 | TRPV1 (0.53) | ALOX5MAPTTRPM8CYP1A2CYP2C19 | |
| SCHEMBL5772744 | 0.68 | ALOX5 (0.50) | JAK2JAK3ALDH1A1ALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |