SCHEMBL1126750

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1992161	0.90	MAPT (0.44)	GAANPSR1MAPTALDH1A1RAB9A
	SCHEMBL1989043	0.87	MAPT (0.38)	TP53MAPTPSMD14USP2MMP2
	SCHEMBL1126560	0.86	SIGMAR1 (0.40)	NPSR1MAPTALDH1A1RAB9AUSP2
	SCHEMBL1127042	0.86	POLB (0.45)	GAANPSR1TP53MAPTALDH1A1
	SCHEMBL1127002	0.86	AR (0.40)	GAANPSR1MAPTALDH1A1RAB9A
	SCHEMBL1126468	0.86	TSHR (0.39)	NPSR1MAPTALDH1A1SMN1; SMN2RAB9A
	SCHEMBL30234914	0.86	POLB (0.45)	GAANPSR1TP53MAPTALDH1A1
	SCHEMBL1126696	0.85	MAPT (0.50)	GAANPSR1TP53MAPTALDH1A1
	SCHEMBL1127172	0.82	NPY2R (0.45)	GAAMAPTALDH1A1NPC1SMN1; SMN2
	SCHEMBL1999344	0.78	MAPT (0.41)	GAANPSR1MAPTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.