SCHEMBL1126468

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126928	0.89	MAPT (0.39)	TSHRMAPTASAH1HTR2AHTR2C
	SCHEMBL1127002	0.88	AR (0.40)	TSHRMAPTFGFR1FGFR2KDR
	SCHEMBL1126560	0.88	SIGMAR1 (0.40)	TSHRMAPTFGFR1FGFR2KDR
	SCHEMBL1126750	0.86	GAA (0.37)	MAPTNPSR1ALDH1A1RAB9AKDM4E
	SCHEMBL1992161	0.85	MAPT (0.44)	MAPTLMNANPSR1MEN1KMT2A
	SCHEMBL1126788	0.84	KDM4E (0.46)	TSHRMAPTMEN1KMT2AALDH1A1
	SCHEMBL30234914	0.83	POLB (0.45)	TSHRMAPTLMNAHPGDNPSR1
	SCHEMBL1127042	0.83	POLB (0.45)	TSHRMAPTLMNAHPGDNPSR1
	SCHEMBL1994130	0.82	MAPT (0.39)	TSHRMAPTASAH1FGFR1FGFR2
	SCHEMBL1126883	0.78	SIGMAR1 (0.38)	MAPTHTR2AHTR2CSLC6A4DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.