SCHEMBL1992161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126750	0.90	GAA (0.37)	MAPTALDH1A1NPSR1GAATDP1
	SCHEMBL1999344	0.87	MAPT (0.41)	MAPTALDH1A1P2RY1HTTNPSR1
	SCHEMBL1126487	0.86	MAPT (0.51)	MAPTALDH1A1HTTNPSR1KMT2A
	SCHEMBL30234914	0.85	POLB (0.45)	MAPTALDH1A1HTTNPSR1KMT2A
	SCHEMBL1126468	0.85	TSHR (0.39)	MAPTALDH1A1NPSR1KMT2AMEN1
	SCHEMBL1126560	0.85	SIGMAR1 (0.40)	MAPTALDH1A1NPSR1KMT2AMEN1
	SCHEMBL1127002	0.85	AR (0.40)	MAPTALDH1A1P2RY1NPSR1KMT2A
	SCHEMBL1127042	0.85	POLB (0.45)	MAPTALDH1A1HTTNPSR1KMT2A
	SCHEMBL1989043	0.78	MAPT (0.38)	MAPTPOLB
	SCHEMBL1126696	0.77	MAPT (0.50)	MAPTALDH1A1HTTNPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.