SCHEMBL1126560

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126883	0.89	SIGMAR1 (0.38)	SIGMAR1TMEM97HRH1HRH3MAPT
	SCHEMBL1127002	0.88	AR (0.40)	MAPTFGFR1FGFR2KDRHTR2C
	SCHEMBL1126468	0.88	TSHR (0.39)	MAPTFGFR1FGFR2KDRHTR2C
	SCHEMBL1126750	0.86	GAA (0.37)	MAPTNPSR1RAB9AUSP2ALDH1A1
	SCHEMBL1992161	0.85	MAPT (0.44)	MAPTMEN1KMT2ALMNANPSR1
	SCHEMBL30234914	0.83	POLB (0.45)	MAPTDRD3TSHRMEN1KMT2A
	SCHEMBL1127042	0.83	POLB (0.45)	MAPTDRD3TSHRMEN1KMT2A
	SCHEMBL1126928	0.78	MAPT (0.39)	MAPTHTR2CDRD3TSHRHTR2A
	SCHEMBL1126921	0.78	MAPT (0.37)	SIGMAR1TMEM97MAPTFGFR1FGFR2
	SCHEMBL1989043	0.76	MAPT (0.38)	MAPTATMUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.