Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 8/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500354 | 0.81 | PRKAB2 (0.41) | MCL1BCL2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1126656 | 0.71 | KMT2A (0.39) | ALDH1A1KMT2ANPSR1MAPK1AKR1C3 | |
| SCHEMBL9816497 | 0.69 | MCL1 (0.67) | MCL1BCL2ALDH1A1 | |
| SCHEMBL16111747 | 0.68 | LMNA (0.48) | ALDH1A1LMNAGAATSHRHTT | |
| SCHEMBL1126618 | 0.68 | EGFR (0.40) | MAPK1HPGD | |
| SCHEMBL1126583 | 0.66 | JAK2 (0.48) | ALDH1A1MAPK1MAPTHPGD | |
| SCHEMBL8207134 | 0.65 | HCAR2 (0.37) | MCL1BCL2GPR17ALDH1A1LMNA | |
| SCHEMBL1127003 | 0.65 | GPR17 (0.54) | GPR17ALDH1A1 | |
| SCHEMBL6574519 | 0.65 | PLA2G7 (0.39) | ALDH1A1KMT2AMAPK1TSHRHTT | |
| SCHEMBL20749518 | 0.65 | TAAR1 (0.52) | ALDH1A1KMT2ALMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |