Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127376 | 0.90 | LMNA (0.40) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1127778 | 0.83 | LMNA (0.39) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1126902 | 0.80 | LMNA (0.38) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1126894 | 0.78 | LMNA (0.48) | LMNARAB9AALDH1A1TP53NPC1 | |
| SCHEMBL1126936 | 0.78 | CSF1R (0.39) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1127366 | 0.74 | LMNA (0.37) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1127408 | 0.73 | RAB9A (0.39) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1127422 | 0.72 | RAB9A (0.41) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1127399 | 0.72 | LMNA (0.35) | LMNARAB9AALDH1A1CSF1RCYP1A2 | |
| SCHEMBL1127186 | 0.71 | MTNR1A (0.45) | LMNARAB9AALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |