SCHEMBL1127213

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127228	0.86	FAAH (0.40)	NPC1PORCNFAAHEPHX2LTA4H
	SCHEMBL1991279	0.79	DRD4 (0.39)	NPC1RAB9ACYP3A4CYP2D6SMN1; SMN2
	SCHEMBL15161945	0.78	HTR1A (0.44)	CYP3A4SMN1; SMN2MAPTKDM4EALDH1A1
	SCHEMBL1990047	0.78	HCRTR1 (0.38)	NPC1PORCNRAB9ACYP3A4CYP2D6
	SCHEMBL1996541	0.77	REV1 (0.40)	USP2CYP3A4SMN1; SMN2MAPTKDM4E
	SCHEMBL1990333	0.77	MAPKAPK2 (0.41)	NPC1RAB9ACYP3A4MAPTALDH1A1
	SCHEMBL1126855	0.76	RAB9A (0.41)	NPC1RAB9AMAPTWNT3AALDH1A1
	SCHEMBL1989640	0.76	HCRTR1 (0.39)	NPC1USP2RAB9ACYP3A4CYP2D6
	SCHEMBL1127378	0.76	HPGD (0.41)	NPC1RAB9ASMN1; SMN2MAPTTP53
	SCHEMBL1126711	0.76	CFTR (0.37)	NPC1USP2RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.